Transfer of a quality-controlled mycoplasma capricolum subsp. capricolum master seed and vaccine production technology from CIRAD to AU-PANVAC
Programs and partnerships
Lead institution(s)
Summary
CIRAD, a French agricultural research and international cooperation organization, holds a candidate seed for the production of an improved contagious caprine (goat) pleuropneumonia (CCPP) vaccine.Read more
CIRAD, a French agricultural research and international cooperation organization, holds a candidate seed for the production of an improved contagious caprine (goat) pleuropneumonia (CCPP) vaccine. This fast-growing strain, which is proposed as a replacement of the current seed, has resulted in at least a threefold increase in yield of specific mycoplasma antigens, shorter culture time and less supplements in the medium necessary for growth, while the efficacy of the vaccine was not affected. Safety and stability improvements have also been added to the new vaccine. This strain and vaccine production technology is now being transferred to the Pan African Veterinary Vaccine Center of the African Union (AU-PANVAC) to secure the availability of the improved vaccine to manufacturers in Africa for the benefit of African farmers.
The main objectives of this project are to support: the production and quality control of a parental stock of the new strain that will constitute the master seed for vaccine production in Africa; the transfer of the master seed stock from CIRAD to AU-PANVAC; and the organization of a technical visit of CIRAD staff to PANVAC to engage in discussions and prepare subsequent collaborative work on vaccine formulation, assessment of vaccine thermostability and shelf life, and validation of a routine method for quality control.
About the partnership
