Preventing Zika disease with novel vector control approaches
The highest numbers of dengue cases in Latin America in the last few years have occurred in Brazil, Colombia, and Mexico. These countries have also faced outbreaks of chikungunya (2014-2015) and Zika (2015-2016). All three diseases are transmitted by the same mosquito vector, the aedes aegypti. The University of Ceará, Fundacion Santa Fe de Bogotá, and University of Yucatán have implemented vector control strategies to significantly reduce aedes aegypti.
This proposal aims to scale up participatory interventions targeting the surveillance, prevention, and control of aedes-transmitted diseases in three municipalities, namely Fortaleza (Brazil), Armenia (Colombia), and Merida (Mexico). Multidisciplinary teams will collect epidemiological and entomological indicators at the beginning, mid-term, and end of the project in a household sample of the intervention. The project will also assess the governance outcomes, and the costs and cost-effectiveness of the scaled intervention compared to the routine vector control program. A complementary feature will be the design and implementation of an innovative surveillance system that will engage the community to improve case detection.
Qualitative methods will be used to assess the acceptance of the intervention and to describe factors affecting the scaling up. State and municipal agencies, as well as NGOs, community-based organizations, and academic institutions will co-lead the scale-up of the interventions. Local and national resources have been committed to the implementation of the project. During the previous work of the principal research institutions in the three cities, strong links were developed with relevant strategic stakeholders that will facilitate implementation. The project is expected to make a significant contribution to the prevention of Zika, chikungunya and dengue disease through novel vector control and surveillance interventions that are potentially applicable in many other countries.
Project ID
108412
Project Status
Completed
End Date
Duration
36 months
IDRC Officer
Roberto Bazzani
Total Funding
CA$ 999,100.00
Location
Brazil
Colombia
Mexico
Programs
Global Health
Global Health
Institution Country
Colombia
Project Leader
Gabriel Dr. Carrasquilla
Institution
Fundación Santa Fe de Bogotá
Institution Website
Outputs
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Protección de la vivienda contra la infestación del aedes aegypti en tiempos de COVID-19 Informes
Author(s): Saide, Pablo Manrique, Pavia, Norma Language: Spanish |
Prevención de la enfermedad del zika mediante nuevos abordajes de control vectorial : informe técnico final Informes
Author(s): Carrasquilla, Gabriel, Saide, Pablo Manrique, Caprara, Andrea, Serna, Mónica Marcela Jiménez Language: Spanish |
Vivência educativa de acadêmicos de medicina no minicurso “a abordagem eco-bio-social e a vigilância ativa na prevenção e controle do aedes aegypti” : um relato de experiência Article
Author(s): Barakat, Roberta Duarte Maia, Caprara, Andrea, Macêdo, Suyanne Freire de, Ferreira, José Luís Paiva de Mendonça, Santos, Thanamy de Andrade Language: Portuguese |
Efficacy of long-lasting insecticidal nets with declining physical and chemical integrity on Aedes aegypti (diptera : culicidae) Article
Fitting long-lasting insecticidal nets (LLIN) as screens on doors and windows has a significant impact on indoor adult Aedes aegypti, with entomological reductions measured in a previous study being significant for up to two years post-installation, even in the presence of pyrethroid-resistant Aedes populations. The study used bioassays (0, 6, and 12 months), which confirmed that LLIN residual activity decreased over time. However, the study demonstrates that the remaining chemical effect after field conditions still contributes to killing/repelling mosquitoes. LLIN screening from the neighborhood Juan Pablo II in Merida (Yucatan State, Mexico) were randomly selected. Merida is highly endemic for dengue and other Aedes-borne viruses. Author(s): Herrera-Bojórquez, Josué, Trujillo-Peña, Emilio, Vadillo-Sánchez, José, Riestra-Morales, Martin, Che-Mendoza, Azael, Delfín-González, Hugo, Pavía-Ruz, Norma, Arredondo-Jimenez, Juan, Santamaría, Erika, Flores-Suárez, Adriana E., Vazquez-Prokopec, Gonzalo, Manrique-Saide, Pablo Language: English |
Intervenção eco-bio eocial em ambientes escolares com crianças do ensino fundamental para vigilância participativa no combate ao Aedes aegypti Brief
Author(s): Silva, Kellyanne Abreu, Borges de Vasconcelos, Renata, Balacó, Francisca Claudina Fernandes Alves, Martins, Ana Beatriz Souza, Vasconcelos de Sousa, Izautina, Caprara, Andrea Language: Portuguese |
Características de la vivienda y su entorno asociados a la presencia de casos de dengue, chikungunya y zika en Mérida, Yucatán durante el periodo 2015 - 2017 Study
Author(s): Rodríguez, Azael Cohuo Language: Portuguese |
Insecticide-treated house screening protects against Zika-infected Aedes aegypti in Merida, Mexico Article
There is strong and unquestionable epidemiological evidence of the protective efficacy of insecticide treated screens (ITS) against an arboviral disease of major relevance. Houses with ITS were 79-85% less infested with Aedes females than control houses during the peak of the zika epidemic, an effect that was significant up to a year. A similar significant trend was observed for blood-fed Ae. aegypti females (76-82%). Communities strongly accepted the intervention, due to its perceived mode of action, the prevalent risk for Aedes-borne diseases in the area, and the positive feedback from neighbours receiving ITS. The paper provides details of the study. Author(s): Pablo, Manrique Saide, Herrera-Bojórquez, Josue, Anuar, Medina-Barreiro, Emilio, Trujillo-Peña, Josué, Villegas-Chim, Nina, Valadez-González, Ahmed, M.M. Ahmed, Hugo, Delfín-González, Jorge, Palacio-Vargas, Azael, Che-Mendoza, Norma, Pavía-Ruz, Adriana, Flores-Suárez, Gonzalo, Vazquez-Prokopec Language: English |
Implementação de intervenção pautada na abordagem eco-bio-social como estratégia inovadora de controle do Aedes aegypti : relato de experiência Brief
Author(s): Silva, Kellyanne Abreu, Macêdo, Suyanne Freire, Borges de Vasconcelos, Renata, Ferandes, Hélida Melo Conrado, Sousa Vasconcelos, Izautina, Caprara, Andrea Language: Portuguese |
Dinámica poblacional de aedes aegypti (Diptera : Culicidae) en cuatro localidades de Yucatán Estudios
Author(s): Trava, Juan Manuel Chávez Language: Spanish |
Technical document for the implementation of interventions based on generic operational scenarios for Aedes aegypti control Book
Traditional methods to control the Aedes vector have had only a limited and temporary impact on disease prevention, either because they are not very effective or their coverage is limited. This publication provides a framework for planning and implementing Aedes aegypti surveillance, prevention, and vector control activities through risk stratification to support the development of potential operational scenarios at the local level. A comprehensive table provides a snapshot of “Entomological indicators (available methods) and main entomological indexes for A. aegypti surveillance.” Author(s): Saide, Pablo Manrique, Prokopec, Gonzalo Vazquez, Clennon, Julie, Che-Mendoza, Azael, Pan American Health Organization Language: English |
Processo participativo na escolha de territórios para implementação da abordagem eco bio-social no controle do Aedes Aegypti Brief
Author(s): Freire de Macedo, Suyanne, Borges de Vascocelos, Renata, Santos, Gerarlene Ponte Guimaraes, Dantas, Ianny de Assis, Caprara, Andrea Language: Portuguese |
Lagarta pintada, quem foi que te picou? A implementação da abordagem eco-bio-social em ambiente escolar para a vigilância ativa no controle do aedes aegypti Study
Author(s): Barakat, Roberta Duarte Maia Language: Portuguese |
Gestão em saúde : reflexões, diversidades temáticas, teóricas, metodológicas e tecnologias de discentes e docentes em gestão em saúde coletiva Book
Author(s): Jorge, Maria Salete Bessa, Florêncio, Raquel Sampaio, Rodrigues de Souza, Adriano Language: Portuguese |
Formação em abordagem eco-bio-social para o controle do Aedes aegypti : reflexões sobre trabalho em equipe Brief
Author(s): Borges de Vasconcelos, Renata, Silva, Kellyanne Abreu, Fernandes, Hélida Melo Conrado, Vasconcelos, Izautina Sousa, Freire de Macedo, Suyanne, Caprara, Andrea Language: Portuguese |
Relato de experiência de educação em saúde com base na abordagem eco-bio-social em ambiente escolar para a promoção da saúde e o controle do vetor aedes aegypti Training Materials
Author(s): de Macêdo, Suyanne Freire, Barakat, Roberta Duarte Maia, Caprara, Andrea Language: Portuguese |
Desabastecimento e infestação por Aedes : desafios globais à Brief
Author(s): Freire de Macêdo, Suyanne, Silva, Kellyanne Abreu, Borges de Vasconcelos, Renata, Vasconcelos, Izautina Sousa, Caprara, Andrea, Lima, José Wellington de Oliveira Language: Portuguese |
Ambiente escolar e o photovoice : ações de vigilância ativa comunitária para o controle do aedes aegypti Brief
Author(s): Barakat, Roberta Duarte Maia, Caprara, Andrea Language: Portuguese |
Evaluation of insecticide-treated house screening on entomological infestation and arbovirus infection of Aedes aegypti during a Zika transmission period in Merida, Mexico Training Materials
Houses are provided with long-lasting insecticidal nets (LLIN), permanently fixed with aluminium frames on doors and windows. Insecticide-treated house screening (ITS) proved to confer protection which showed 50% less chance of having indoor female Ae. aegypti in comparison with non-protected houses in urban areas of the Mexican cities of Acapulco and Merida. The brochure provides a brief encapsulation of the project and results. The study included the detection of dengue (DENV), chikungunya (CHIKV) and Zika (ZIKV) viruses. All of the project participants perceived effective mosquito reduction and recommend scaling-up of the intervention. Author(s): Manrique-Saide, P., Herrera-Bojórquez, J., Medina-Barreiro, A., Trujillo-Peña, E., Villegas-Chim, J. Language: English |
Potenciais criadouros para Aedes aegypti em áreas endêmicas para dengue : questões culturais ou governamentais? Brief
Author(s): Freire de Macêdo, Suyanne ,, Silva, Kellyanne Abreu, Borges de Vasconcelos, Renata, Vasconcelos, Izautina Sousa, Lima, José Wellington de Oliveira, Caprara, Andrea Language: Portuguese |
Acadêmicos de medicina como intermediadores em minicurso para a formação de escolares na perspectiva da promoção e prevenção das arboviroses : um relato de experiência Brief
Author(s): Filho, Aderval Brígido de Sousa, Santos, Thanamy de Andrade, Araújo, Yuri Quintans, Barakat, Roberta Duarte Maia, Caprara, Andrea Language: Portuguese |
Juntos podemos mejorar el entorno y prevenir es la mejor opción Training Materials
Author(s): Giraldo, Sandra, Jimenez, Monica, Carrasquilla, Gabriel, Cerquera, Dayana, Quintero, Liliana, Ramirez, Harold Language: Portuguese |
Conhecimentos de gestantes e parceiros sobre as arboviroses transmitidas pelo Aedes aegypti Brief
Author(s): Santos, Gerarlene Ponte Guimarães, Silva, Kellyanne Abreu, Farias, Maria Sinara, Fernandes, Hélida Melo Conrado, Vasconcelos, Renata Borges Language: Portuguese |
Expectativas e percepções de profissionais de saúde sobre a formação em abordagem eco-bio-social Brief
Author(s): De Vasconcelos, Renata Borges, Silva, Kellyanne Abreu, Fernandes, Hélida Melo Conrado, De Sousa, Izautina Vasconcelos, De Macêdo, Suyanne Freire, Caprara, Andrea Language: Portuguese |
Manual de instalación y mantenimiento de mallas mosquiteras : instrucciones de reparación Material de formación
Author(s): Bojorquez, Josue Gaspar Herrera, Saide, Pablo Manrique Language: Spanish |
Integração da vigilância à saúde e atenção primária à saúde para o controle do aedes aegypti com a abordagem eco-bio-social Brief
Author(s): Santos, Geralene Ponte Guimarães, Caprara, Andrea, Costa, Rayla Maria Ponte Guimarães, Silva, Kellyanne Abreu, Oliveira, Krysne Kelly De França, Mesquita, Lyvia Patrícia Soares Language: Portuguese |
Frechais e estrutura dos domicílios : mais um desafio para o controle do aedes aegypti na cidade de Fortaleza, Brasil Brief
Author(s): De Macêdo, Suyanne Freire, Gadelha, Francisco Vieira, Silva, Kellyanne Abreu, De Vasconcelos, Renata Borges, Caprara, Andrea, Lima, José Wellington De Oliveira Language: Portuguese |
Social assessment on an integrated intervention for the prevention of Zika and other Aedes-borne diseases in pregnant women and their families in Mexico Brief
Results of the project show that pregnant women can be provided with free or low-cost integrated interventions with methods of known efficacy (topical repellent and insecticide-treated window screens) along with educative strategies, and that they are highly motivated to use these methods to enhance maternal-child health for Zika and other Aedes-borne diseases (ABD). This is a one-page assessment/synopsis of the integrated intervention. Author(s): Manrique-Saide, P., Villegas-Chim, J., Pavía-Ruz, N., Espinosa-Lizama, F., Medina-Várguez, A. Language: English |
Abordagem eco-bio-social como cenário de promoção da saúde em ambiente escolar no combate ao aedes aegypti Paper
Author(s): Barakat, Roberta Duarte Maia, Caprara, Andrea Language: Portuguese |
Envolvimento de profissionais de saúde para participar de uma formação em abordagem eco-bio-social para controlar às arboviroses : relato de experiência Brief
Author(s): Borges de Vasconcelos, Renata, Rodrigues, Maria Iara de Sousa, Silva, Kellyanne Abreu, Feijão, Mayara Júlia Gadelha, Ferreira De Freitas, Alinson Salatiek Language: Portuguese |
Implementação da vigilância participativa na escola : o protagonismo do estudante na vigilância de casos de Dengue, Chikungunya e Zika Report
Author(s): Vasconcelos de Sousa, Izautina, Silva, Kellyanne Abreu, Borges de Vasconcelos, Renata, Fernandes, Hélida Melo Conrado, Balacó, Francisca Claudina Fernandes Alves Language: Portuguese |
Spatio-temporal coherence of dengue, chikungunya and Zika outbreaks in Merida, Mexico Article
Longitudinal Dengue (DENV) data generated patterns indicative of the resulting introduction and transmission patterns of chikungunya (CHIKV) and Zika virus (ZIKV), leading to important insights for the surveillance and targeted control of emerging Aedes-borne viruses. About 42% of the 40,028 DENV cases reported during 2008–2015 clustered in 27% of Merida (Mexico), and these clustering areas were where the first CHIKV and ZIKV cases were reported in 2015 and 2016. Findings from this article open a window to the consideration of spatially-targeted approaches for delivery of vector control interventions and surveillance. Author(s): Bisanzio, Donal, Dzul-Manzanilla, Felipe, Gomez-Dante, Hector, Pavia-Ruz, Norma, Hladish, Thomas J. Language: English |
Abordagem Eco-Bio-Social e princípios fundamentais para o controle de vetores : conhecimento prévio dos profissionais de saúde Brief
Author(s): Borges de Vasconcelos, Renata, Fernandes, Hélida Melo, Silva, Kellyanne Abreu, Vasconcelos de Souza, Izautina, Mesquita, Lyvia Patrícia Soares, Caprara, Andrea Language: Portuguese |
“O prazer de conhecer e que fez um novo raio de sol brilhar em nosso amanhecer” : os sentidos atribuídos a formação eco-bio-social para o controle do aedes aegypti Study
Author(s): De Vasconcelos, Renata Borges Language: Portuguese |
Vigilância participativa nas ecolas para o controle do aedes aegypti : abordagem eco-bio-social como estratégia de promoção da saúde Study
Author(s): Fernandes, Hélida Melo Conrado Language: Portuguese |
New record of Aedes Albopictus in a suburban area of Merida, Yucatan, Mexico Article
Along with Aedes aegypti (L.), Aedes albopictus has been implicated as a secondary vector for dengue virus, chikungunya virus, and Zika virus in Latin America. The article covers an entomological survey in 2018, in a suburban area of Merida (the largest and capital city in Yucatan). This is the first report of Ae. albopictus in a suburban area of Merida City. A total of 259 specimens were collected. It is important to consider the ecology of Ae. albopictus alongside that of Ae. aegypti when developing vector/disease control programs. Author(s): Contreras-Pereira, Yamili J., Briceno-Mendez, Marcos, Flores-Suarez, Adriana E., Manrique-Saide, Pablo, Palacio-Vergas, Jorge A., Huerta-Jimenez, Heron, Martin-Park, Abdiel Language: English |
Identifying urban hotspots of dengue, chikungunya, and zika transmission in Mexico to support risk stratification efforts : a spatial analysis Article
The study identifies persistent Aedes-borne disease hotspots in Mexican cities. In this spatial analysis, geocoded cases of dengue, chikungunya, and Zika from nine endemic cities were aggregated at the census-tract level. Findings show an overlap between hotspots of 61.7% for dengue and Zika and 53.3% for dengue and chikungunya. Dengue hotspots (2008–16) were significantly associated with those detected during 2017–20 in five of the nine cities. Heads of vector control confirmed hotspot areas as problem zones for arbovirus transmission. This study provides evidence of the overlap of Aedes-borne diseases within geographical hotspots and a methodological framework for the stratification of arbovirus transmission risk. Author(s): Dzul-Manzanilla, Felipe, Correa-Morales, Fabián, Che-Mendoza, Azael, Palacio-Vargas, Jorge, Sánchez-Tejeda, Gustavo Language: English |
Insecticide-treated house screening protects against zika-infected aedes aegypti in Merida, Mexico Article
Houses protected with screens were 80% less infested with Aedes females and very importantly, had significantly less infected female Ae. aegypti during the peak of the Zika epidemic. Integration of house-screening and long-lasting insecticidal nets, known as insecticide treated screening (ITS), can provide simple, safe, and low-tech Aedes aegypti control. Cluster randomised controlled trials in two endemic localities for Ae. aegypti of south Mexico, show that ITS conferred both immediate and sustained impact on indoor-female Ae. aegypti infestations. Such encouraging results require further validation with studies quantifying more epidemiologically-related endpoints, including arbovirus infection in Ae. Aegypti. Author(s): Manrique-Saide, Pablo, Herrera- Bojorquez, Josue, Medina-Barreiro, Anuar, Trujillo-Peña, Emilio, Villegas-Chim, Josue´ Language: English |
Current topics in Zika Book
This book includes a range of topics with regard to epidemiology, clinical manifestations, treatment, and prevention of a wide spectrum of impacts caused by Zika virus in humans, including not only congenital Zika syndrome (CZS) but also entomological aspects. It is organized into two major sections: (1) Clinical Aspects, and (2) Epidemiological and Entomological Aspects. The book provides an in-depth perspective on mosquito borne diseases with a focus on Zika epidemiology and vector control in Latin America. IntechOpen is a leading global publisher of Journals and Books within the fields of Science, Technology and Medicine. Author(s): Language: English |
Dengue, Chikungunya e Zika na gestação : cuidados para um nascimento saudável Brief
Author(s): Santos, Gerarlene Ponte Guimarães Language: Portuguese |
Vigilância participativa da comunidade para o combate das arboviroses transmitidas pelo aedes aegypti em uma intervenção eco-bio-social Paper
Author(s): Silva, Kellyanne Abreu, Borges de Vasconcelos, Renata, Conrado, Hélida Melo, Vasconcelos de Sousa, Izautina, Mesquita, Lyvia Patrícia Soares |
Estimating absolute indoor density of Aedes aegypti using removal sampling Article
Exhaustive removal sampling represents a promising method for quantification of absolute indoor Aedes aegypti density, leading to improved entomological estimates of mosquito distribution. The study describes the use of sequential removal sampling to estimate absolute numbers of indoor resting Aedes in the city of Merida, Mexico. The study was performed in 200 houses based on recent occurrence of Aedes-borne viral illness in residents. The lack of a numerical association between relative and absolute density of adult Ae. aegypti represent a significant gap in vector surveillance. Merida is highly endemic for dengue and other Aedes-borne viruses. Author(s): Koyoc‑Cardena, Edgar, Medina‑Barreiro, Anuar, Cohuo‑Rodriguez, Azael, Pavia‑Ruz, Norma, Lenhart, Audrey, Ayora‑Talavera, Guadalupe, Dunbar, Mike, Manrique‑Saide, Pablo, Vazquez‑Prokopec, Gonzalo Language: English |
Ecobiosocial approach and health promotion at school : building knowledge for community surveillance in Aedes aegypti control Article
The study aims to implement community surveillance actions for Aedes Aegypti vector control in school environments in light of health promotion and eco-bio-social approaches. This qualitative research addresses the assumptions of action research. Recommended as an innovative technology for vector control in Brazil, eco-bio-social approaches play an essential role in the sustainability of combating Aedes Aegypti and the diseases it transmits. The article follows the methodology, data collection and results of the project. Individual and community surveillance and social participation actions are essential to rethink vector control strategies for transmission of Dengue, Chikungunya and Zika diseases. Author(s): Barakat, Roberta Duarte Maia, Caprara, Andrea Language: English |
Effectiveness of an intervention for Aedes aegypti control scaled-up under an intersectoral approach in a Colombian city hyperendemic for dengue virus Article
The study designed a scaled-up community-led Aedes control intervention and assessed it for its capacity to reduce dengue in Girardot, Colombia. Reported dengue cases, and associated factors were analysed from Colombian disease surveillance systems data sets. The differences in dengue incidence among scaling-up phases (pre-implementation vs sustainability) and between treatment groups (intervention and control areas) were modelled. Evidence was found in favour of the intervention, although to maximise impact the scaling-up of the intervention should continue until it covers the remaining sectors. Aedes aegypti is the principal vector of dengue, chikungukya, Zika and yellow fever and is found on all continents except Antarctica. Author(s): Quintero, Juliana, Pulido, Nicolás Ronderos, Logan, James, Ant, Thomas, Bruce, Jane, Carrasquilla, Gabriel Language: English |