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Enabling Business and Technologies to Contribute to the Control of Mosquito-Borne Diseases in Latin America

Aedes mosquito-transmitted illnesses, namely dengue, chikungunya, and Zika, have become a major burden of disease in Latin America and the Caribbean, where vector control programs have not been able to reduce the risk of disease transmission.

IDRC and the Sao Paulo Research Foundation have partnered to promote and assess the role of small businesses in the development of new Aedes mosquito control technologies. Two research studies will take place in Mexico, where 60% of the territory, representing more than 50 million people, presents favorable conditions for the incidence of the Aedes mosquito. These studies will generate scientific evidence to support house screening as an effective and affordable vector tool in the city of Merida. It will also assess the efficacy, acceptability, and biosecurity of a paint that has the effect of prolonged residual insecticide in the city of Pochutla.

Local partners Universidad Autónoma de Yucatán and CodeQuim, a vector control company, will implement the project. Senior researchers, small businesses, decision-makers and community representatives will be involved in both studies. Cost-effectiveness studies will assess the affordability of the proposed vector control tools. Subject to results, both the house screening and insecticide paint are promising tools to be applied in the context of integrated vector management. They are expected to contribute to national and/or state-level public health efforts to reduce the risk of Aedes-transmitted diseases and to be replicated in other Mexican cities. The project will document lessons learned about the role of small business in enhancing community access to vector control tools and assess the factors that influence their capacity to develop and speed up the time-to-market of Aedes control technologies.

Project ID
109071
Project Status
Active
End Date
Duration
24 months
IDRC Officer
Roberto Bazzani
Total Funding
CA$ 535,300.00
Location
Mexico
Programs
Global Health
Global Health
Project Leader
CODEQUIM
Institution
CODEQUIM
Institution Country
Mexico
Project Leader
Jorge Méndez Galván
Institution
CODEQUIM, SOCIEDAD ANÓNIMA DE CAPITAL VARIABLE
Institution Country
Mexico
Project Leader
Pablo Manrique
Institution
Universidad Autónoma de Yucatán

Outputs

Evaluación de una pintura con insecticida microencapsulado para el control de Aedes Aegypti

Evaluación de una pintura con insecticida microencapsulado para el control de Aedes Aegypti

Informes

Author(s): Méndez Galván, Jorge, Azamar Cruz, Erik, Villegas Trejo, Alejandro, Pruñonosa Santana, Javier, Duarte Elguea, Erika, Luis Alarcón, José

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Language: Spanish

Protective effect of house screening against indoor aedes aegypti in Mérida, Mexico : a cluster randomised controlled trial

Protective effect of house screening against indoor aedes aegypti in Mérida, Mexico : a cluster randomised controlled trial

Article

Objective: To evaluate the protective effect of house screening (HS) on indoor Aedes aegypti infestation, abundance and arboviral infection in Merida, Mexico. Methods: In 2019, we performed a cluster randomised controlled trial (6 control and 6 intervention areas: 100 households/area). Intervention clusters received permanently fixed fiberglass HS on all windows and doors. The study included two cross-sectional entomologic surveys, one baseline (dry season in May 2019) and one post-intervention (PI, rainy season between September and October 2019). The presence and number of indoor Aedes females and blood-fed females (indoor mosquito infestation) as well as arboviral infections with dengue (DENV) and Zika (ZIKV) viruses were evaluated in a subsample of 30 houses within each cluster. Results: HS houses had significantly lower risk for having Aedes aegypti female mosquitoes (odds ratio [OR] = 0.56, 95% CI 0.33–0.97, p = 0.04) and blood-fed females (OR = 0.53, 95% CI 0.28–0.97, p = 0.04) than unscreened households from the control arm. Compared to control houses, HS houses had significantly lower indoor Ae. Aegypti abundance (rate ratio [RR] = 0.50, 95% CI 0.30–0.83, p = 0.01), blood-fed Ae. Aegypti females (RR = 0.48, 95% CI 0.27–0.85, p = 0.01) and female Ae. aegypti positive for arboviruses (OR = 0.29, 95% CI 0.10–0.86, p = 0.02). The estimated intervention efficacy in reducing Ae. Aegypti arbovirus infection was 71%. Conclusions: These results provide evidence supporting the use of HS as an effective pesticide-free method to control house infestations with Aedes aegypti and reduce the transmission of Aedes-transmitted viruses such as DENV, chikungunya (CHIKV) and ZIKV.

Author(s): Manrique- Saide, Pablo, Herrera-Bojórquez, Josué, Villegas-Chim, Josué, Puerta- Guardo, Henry, Ayora-Talavera, Guadalupe

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Language: English

Improving Aedes aegypti control by enhancing community access to house-screening

Improving Aedes aegypti control by enhancing community access to house-screening

Report

Houses with house-screening (HS) compared to regular netting/unprotected households, had significatively lower risk for having Ae. aegypti female mosquitoes (OR=0.56, 95% C. I. 0.33-0.99) and blood-fed females (OR=0.53, 95% C. I. 0.28-0.97). All project participants were satisfied with the installation process and positive about the efficacy because of perceived significant reductions of mosquito in their houses (>80%). All participants recommended scaling up of the intervention. The technical report provides details of screen installation, participant perspectives, project implementation, cost-benefit analysis and findings. Urban improvements that reduce mosquito populations, especially disease vectors are an important component of sustainable development. The report is in English and Spanish.

Author(s): Saide, Pablo Manrique, Ruz, Norma Pavía

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Language: English