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Collaborative One Health Research Initiative on Epidemics (COHRIE) 

COHRIE generated evidence and practical approaches to strengthen epidemic prevention and response through One Health. 

Four locally led research teams across nine countries in Latin America and sub-Saharan Africa explored how One Health approaches can strengthen epidemic prevention, preparedness and response. 

Funded by IDRC from 2021 to 2026, the CA$18-million Collaborative One Health Research Initiative on Epidemics (COHRIE) supported interdisciplinary research at the intersection of human, animal and environmental health. Each project was rooted in its local context, engaged communities and considered how gender and equity shape epidemic risks and responses. 

Why COHRIE matters

One Health recognizes that the health of people, animals and the environment is interconnected. Preventing and responding to infectious diseases that spread between animals and humans requires collaboration across sectors, particularly in places where environmental change and interactions between people and animals increase the risk of outbreaks. 

Communities are often the first to see signs of emerging health threats. Yet local knowledge and experience can be disconnected from the institutions responsible for epidemic prevention and response. COHRIE explored how locally led research, community participation and stronger coordination across sectors can help bridge these gaps. 

What COHRIE achieved

Faster reporting through community-led surveillance. In West Africa, 49 Community Action Networks helped reduce the time to report potential incidents of animal-to-human disease transmission from an average of 10 days to three. In Uganda, Community One Health Volunteers monitored animal health in their communities and reported incidents directly to national authorities, enabling earlier intervention to help prevent outbreaks.  

Stronger coordination across sectors. In Guinea and the Democratic Republic of the Congo, the DOPERAUS project brought together human, animal and environmental health actors to identify health priorities and coordinate epidemic prevention and response. These processes supported the decentralization and operationalization of One Health platforms in both countries. 

Greater recognition of Indigenous knowledge and sovereignty. Research with Indigenous communities in the Amazon showed how traditional knowledge, community organization, food systems and territorial sovereignty contribute to health and resilience. One Amazon's research and policy engagement contributed to Colombia's adoption of the Indigenous Intercultural Health System as national policy in 2025. 

Stronger collaboration across disciplines and countries. COHRIE brought research teams together to synthesize evidence and share approaches across countries and disciplines. Cross-project collaboration on gender and community participation generated new insights and strengthened connections among One Health researchers. 

Impact briefs

Drawing on evidence and learning across the four projects, three COHRIE impact briefs that synthesize key results and lessons for One Health research, policy and practice were developed. 

An overview of COHRIE's key contributions and lessons for future One Health research and action.

Strengthening epidemic prevention and response through locally led One Health research 

An overview of COHRIE's key contributions and lessons for future One Health research and action.

Lessons on meaningful community participation in One Health research, policy and practice.

Partnering with communities for stronger epidemic prevention and response 

Lessons on meaningful community participation in One Health research, policy and practice. 

 

Insights on integrating gender and equity into One Health research and implementation.

One Health research and practice through a gender lens 


Insights on integrating gender and equity into One Health research and implementation. 

 

 

Lessons for future One Health research and action

COHRIE's experience points to three lessons for future One Health research, policy and practice: 

  • Support local leadership. Effective One Health approaches need to be grounded in local priorities and co-created with research teams, communities and institutions closest to the challenges. 
  • Strengthen cross-sector collaboration. Sustained collaboration among human, animal and environmental health actors can strengthen research, preparedness and response. 
  • Build communities of practice. Opportunities for researchers from different disciplines, countries and contexts to exchange knowledge and approaches can strengthen One Health research and its use. 

COHRIE's findings also point to the need for continued support for community-led surveillance, stronger coordination across sectors and further research on how Indigenous knowledge, territorial sovereignty and food security contribute to resilience in different contexts. 

Explore the research

A One Health assessment of emerging epidemic threats and resilience among Amazonian Indigenous peoples

One Amazon - Colombia, Ecuador and Peru 

A One Health assessment of emerging epidemic threats and resilience among Amazonian Indigenous peoples 

Working with Indigenous communities and organizations, One Amazon examined how traditional knowledge, food systems and territorial sovereignty contribute to health and resilience. Its research and policy engagement contributed to Colombia's adoption of the Indigenous Intercultural Health System as national policy in 2025. 

Decentralize and operationalize the One Health platforms

DOPERAUS - Guinea and the Democratic Republic of the Congo 

Decentralize and operationalize the One Health platforms  

DOPERAUS strengthened subnational One Health coordination by bringing together human, animal and environmental health actors to identify priorities and coordinate epidemic prevention and response. Its work supported the roll-out of One Health platforms in both countries. 


 

Surveillance, control and prevention of neglected zoonotic diseases

COHRIE-Uganda - Uganda 

Surveillance, control and prevention of neglected zoonotic diseases 

COHRIE-Uganda investigated neglected zoonotic diseases at the human-animal-wildlife interface in Uganda's cattle corridor. It developed a Community One Health Volunteer model that strengthened local surveillance and connected community reporting with national health, agriculture and wildlife authorities. 


 

West African One Health actions for understanding, preventing and mitigating outbreaks

WAOH - Guinea, Liberia, Nigeria and Sierra Leone 

West African One Health actions for understanding, preventing and mitigating outbreaks 

WAOH examined how environmental change, land use and social factors influence the emergence and spread of diseases such as Ebola and Lassa fever. The project combined community-led surveillance, gender-responsive research and multisectoral collaboration to strengthen epidemic prevention and response across four West African countries. 

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